Your choice. Your birth control

About the patch

The patch can be placed on your upper outer arm, abdomen, buttock or back in a place where it won’t be rubbed by tight clothing. Do not place on your breasts or the same skin area as the previous patch. Only apply to clean, dry skin. Do not use lotions, creams, oils, powders, or makeup at the patch site. Check the patch every day to make sure all edges are sticking correctly. Your patch must stick securely to your skin to work properly. Do not try to reapply a patch if it is no longer sticky. Do not tape or wrap the patch to your skin. See how to apply it »

Where to apply your birth control
Where to apply your birth control

Size up the patch

Size comparison of the Xulane Patch
Size comparison of the Xulane Patch™
  • How does the patch work?

    Xulane is a birth control patch with two female hormones: an estrogen called ethinyl estradiol, and a progestin called norelgestromin. This type of combination hormonal contraception prevents pregnancy, and can be just as effective as the pill when used as directed. Your chance of getting pregnant depends on how well you follow the directions for using Xulane. The better you follow the directions, the less chance you have of getting pregnant.

    Xulane may be less effective in preventing pregnancy in women who weigh 198 lbs (90 kg) or more. Hormonal birth control methods help to lower the chances of becoming pregnant. They do not protect against HIV infection (AIDS) and other sexually transmitted infections.

    Hormones from the patch enter the bloodstream and are processed by the body differently than hormones from birth control pills. You will be exposed to about 60% more estrogen if you use the patch than if you use a typical birth control pill containing 35 micrograms of estrogen. In general, increased estrogen may increase the risk of side effects, including blood clots. Please see the Important Safety Information below and click here for the full Patient information and Patient Instructions for Use.

  • How do I start the patch?

    If you are not currently using hormonal birth control, there are two options for starting the patch. Choose the option that is right for you:

    First day start

    Apply your first patch during the first 24 hours of your menstrual period.

    Sunday start

    Apply your first patch on the first Sunday after your menstrual period begins. Use a non-hormonal contraceptive method of birth control, such as a condom and spermicide or diaphragm and spermicide, for the first 7 days of your first cycle only. If your period starts on Sunday, apply your first patch that day, and no backup birth control is needed.

    If switching from the pill or vaginal contraceptive ring to the patch

    Complete your current pill cycle or vaginal ring cycle. Apply your first patch on the day you would normally start your next pill or insert your next vaginal ring. If you do not get your period within 1 week after taking your last active pill or removing your last vaginal ring, check with your healthcare provider to make sure you are not pregnant. You may still go ahead and start the patch for contraception. If you apply your patch more than 1 week after taking your last active pill or removing your last vaginal ring, use a non-hormonal contraceptive method with the patch for the first 7 days of patch use.

    If using after childbirth

    If you are not breastfeeding, wait 4 weeks before using the patch and use a non-hormonal contraceptive method of birth control, such as a condom and spermicide or diaphragm and spermicide, for the first 7 days of your first cycle only. If you have had sex since your baby was born, wait for your first period, or see your healthcare provider to make sure you are not pregnant before starting the patch.

    If using after abortion or miscarriage

    You may start the patch immediately after a miscarriage or abortion that occurs in the first 12 weeks (first trimester) of pregnancy. You do not need to use another contraceptive method.

    If you do not start the patch within 5 days after a first trimester miscarriage or abortion, use a non-hormonal contraceptive method of birth control, such as a condom and spermicide or diaphragm and spermicide, while you wait for your period to start.You should follow the instructions above for First day start or Sunday start based on what's right for you, and read the full Patient Information for starting Xulane.

    If you are starting the patch after a miscarriage or abortion that occurs after the first 12 weeks of pregnancy (second trimester), wait 4 weeks before using the patch and use a non-hormonal contraceptive method of birth control, such as a condom and spermicide or diaphragm and spermicide, for the first 7 days of your first cycle only. If you have had sex since your miscarriage or abortion, wait for your first period, or see your healthcare provider to make sure you are not pregnant before starting the patch.

  • How do I apply the patch?

    Use Xulane exactly as your healthcare provider tells you to use it. Place the patch on your upper outer arm, abdomen, buttock or back in a place where it won’t be rubbed by tight clothing. For example, you should not place it under the waistband of clothing. Do not place on your breasts, cut or irritated skin, or the same skin area as your last patch. Do not cut, damage, or alter the Xulane Patch in any way. Patch images shown below are for illustration purposes only and do not represent the actual Xulane Patch.

    Before applying

    Make sure your skin is clean and dry. Don’t use lotions, creams, oils, powders, or makeup at the patch site. This may cause the patch to fail to stick properly or become loose.

    Applying the patch

    Applying the Xulane Patch™: Step 1

    Tear open the pouch at the top edge and one side edge. Peel open the foil pouch and gently remove the contents of the foil pouch and discard the additional pieces of film above and below the patch.

    Applying the Xulane Patch™: Step 2

    Peel away half of the clear plastic. Avoid touching the sticky surface with your fingers.

    Applying the Xulane Patch™: Step 3

    Apply the sticky side of the patch on your clean, dry skin. Remove the other half of the clear plastic and attach the entire patch to your skin.

    Applying the Xulane Patch™: Step 4

    Press firmly on the patch with the palm of your hand for 10 seconds, making sure that the whole patch sticks to your skin. Run your fingers over the entire surface area to smooth out any “wrinkles” around the outer edges of the patch.

    Check your patch every day to make sure all edges are sticking correctly.

  • When do I change it?

    Wear one Xulane Patch at a time. Make sure you remove your old patch before applying your new patch. Do not skip using any patches, even if you do not have sex often. Xulane is applied in a 4-week cycle:

    • Apply your patch one time each week for 3 weeks (21 total days).
    • Apply each new patch on the same day of the week. This day will be your “Patch Change Day.” For example, if you apply your first patch on a Monday, all of your patches should be applied on a Monday.
    • Do not apply your patch during week 4. Make sure you remove your old patch. This is your patch-free week. Your menstrual period should start during your patch-free week.
    • Begin a new 4-week cycle by applying a new patch on the day after week 4 ends. Repeat the cycle of 3 weekly applications followed by a patch-free week.
    • Your patch should never be off for more than 7 days in a row. If your patch is off for more than 7 days in a row and you have sex during this time, you could become pregnant.
    • If you miss a period you might be pregnant. Some women miss their periods or have light periods on hormonal birth control methods even when they are not pregnant. Call your healthcare provider if you miss one period and have not used your patch every day or you miss two periods in a row.

    To throw away the Xulane patch, fold the sticky side of the patch together, place it in a sturdy child-proof container, and place the container in the trash. Used Xulane patches should not be flushed in the toilet.

    If your patch becomes uncomfortable or your application site is red, painful, or swollen, remove your patch and apply a new patch to a new location until your next “Patch Change Day.”

    When to change your birth control
  • What if I forget to change it?

    If you forget to change or remove your patch…

    At the start of any patch cycle (Week 1, Day 1):

    You could become pregnant. You must use a backup contraception method for 7 days. Apply the first patch of your new cycle as soon as you remember. You now have a new “Patch Change Day” and a new Day 1.

    In the middle of your patch cycle (Week 2 or Week 3):

    If you forget to change your patch for 1 or 2 days, apply a new patch as soon as you remember. Apply your next patch on your normal “Patch Change Day.” No backup contraception method is needed.

    If you forget to change your patch for more than 2 days, you could become pregnant. Start a new 4-week cycle as soon as you remember by putting on a new patch. You now have a different “Patch Change Day” and a new Day 1. You must use a backup contraception method for the first 7 days of your new cycle.

    At the end of your patch cycle (Week 4):

    If you forget to remove your patch, take it off as soon as you remember. Start your next cycle on your normal “Patch Change Day,” the day after Day 28. No backup contraception method is needed.

    At the start of your next patch cycle:

    You could become pregnant. Apply the first patch of your new cycle as soon as you remember. You now have a new “Patch Change Day” and a new Day 1. Use a non-hormonal backup contraception method, such as a condom and spermicide or diaphragm and spermicide, for the first 7 days of your new 4-week patch cycle.

    If you have trouble remembering to change your patch, talk to your healthcare provider about how to make patch changing easier or about using another method of contraception.  

  • What if it becomes loose or falls off?

    Your patch must stick securely to your skin to work properly. Do not try to reapply the patch if it is no longer sticky, if it has become stuck to itself or another surface, or if it has other material stuck to it. Do not tape or wrap the patch to your skin or reapply a patch that is partially adhered to clothing.

    If your patch edge lifts up:

    Press down firmly on the patch with the palm of your hand for 10 seconds, making sure that the whole patch sticks to your skin. Run your fingers over the entire surface area to smooth out any “wrinkles” around the edges of the patch. If your patch does not stick completely, remove it and apply a new patch. Do not tape or wrap the patch to your skin or reapply a patch that is partially stuck to clothing. 

    If your patch has been off or partially off:

    For less than 1 day, try to reapply it. If the patch does not stick completely, apply a new patch immediately. No backup contraception is needed and your “Patch Change Day” will stay the same.

    For more than 1 day or if you are not sure for how long, you could become pregnant. To reduce this chance, apply a new patch and start a new 4-week cycle. You will now have a new “Patch Change Day.” Use a non-hormonal backup contraception method, such as a condom and spermicide or diaphragm and spermicide, for the first week of your new 4-week patch cycle.

    If your patch becomes uncomfortable or your application site is red, painful or swollen:

    Change your patch. Remove your patch and apply a new patch to a new location until your next “Patch Change Day.”

 

INDICATION AND USAGE
  • Xulane® is a prescription contraceptive patch used for the prevention of pregnancy in women who choose to use a transdermal patch.

Limitation of Use:

  • Xulane may not be as effective in women weighing more than 198 lbs. (90 kg). If you weigh more than 198 lbs. (90 kg), talk to your healthcare professional about which method of birth control is right for you.

Hormonal birth control methods help to lower the chances of becoming pregnant. They do not protect against HIV infection (AIDS) and other sexually transmitted infections.

IMPORTANT SAFETY INFORMATION

Boxed WARNING

What is the most important information I should know about Xulane?

Do not use Xulane if you smoke cigarettes and are over 35 years old. Smoking increases your risk of serious cardiovascular side effects from hormonal birth control methods, including death from heart attack, blood clots or stroke. This risk increases with age and the number of cigarettes you smoke.

Women 15 to 44 years of age who use Xulane may have an increased risk of blood clots compared to women who use certain birth control pills.

You will be exposed to about 60% more estrogen if you use Xulane than if you use a typical birth control pill containing 35 micrograms of estrogen. In general, increased estrogen may increase the risk of side effects, including blood clots.

See full Prescribing Information for complete Boxed WARNING.

Who should not use Xulane?

Do not use Xulane if you:

  • Smoke and are over 35 years old
  • Have or have had blood clots in your arms, legs, eyes or lungs
  • Have an inherited problem that makes your blood clot more than normal
  • Have had a stroke
  • Have had a heart attack
  • Have certain heart valve problems or heart rhythm problems that can cause blood clots to form in the heart
  • Have high blood pressure that medicine cannot control
  • Have diabetes with kidney, eye, nerve, or blood vessel damage
  • Have had certain kinds of severe migraine headaches with aura, numbness, weakness or changes in vision, or have any migraine headaches if you are over age 35
  • Have liver disease, including liver tumors (benign or cancerous)
  • Have unexplained vaginal bleeding
  • Are pregnant or think you may be pregnant. However, Xulane is not known to cause birth defects when used by accident during pregnancy.
  • Have had breast cancer or any cancer that is sensitive to female hormones

Hormonal birth control methods may not be a good choice for you if you have ever had jaundice (yellowing of the skin or eyes) caused by pregnancy or related to previous use of hormonal birth control.

Tell your healthcare professional if you have ever had any of the above conditions. Your healthcare professional may recommend another method of birth control.

Before you use Xulane tell your healthcare professional:

  • About all your medical conditions.
  • If you are pregnant or think you are pregnant.
  • If you are scheduled for surgery. Xulane may increase your risk of blood clots after surgery. You should stop using your Xulane patch at least 4 weeks before you have surgery and not restart it until at least 2 weeks after your surgery.
  • If you are or will be inactive or immobilized for a long period of time.
  • If you are scheduled for any laboratory tests. Certain blood tests may be affected by hormonal birth control methods.
  • Are breastfeeding or plan to breastfeed. Hormonal birth control methods that contain estrogen, like Xulane, may decrease the amount of milk you make. A small amount of hormones from the Xulane patch may pass into your breast milk. Consider another method of birth control until you are ready to stop breastfeeding.
  • If you plan to start or resume Xulane after child birth. The risk of blood clots is increased for a period of time after childbirth. If you are not breastfeeding, wait 4 weeks before using Xulane.

Tell your healthcare professional about all medicines and herbal products that you take.

Some medicines and herbal products may make hormonal birth control less effective, including, but not limited to:

  • certain seizure medicines (carbamazepine, felbamate, oxcarbazepine, phenytoin, rufinamide, and topiramate)
  • aprepitant
  • barbiturates
  • bosentan
  • griseofulvin
  • certain combinations of HIV medicines (nelfinavir, ritonavir, ritonavir-boosted protease inhibitors)
  • certain non-nucleoside reverse transcriptase inhibitors (nevirapine)
  • rifampin and rifabutin
  • St. John’s wort

Use another birth control method (such as a condom and spermicide or diaphragm and spermicide) when you take medicines that may make the Xulane patch less effective.

Some medicines and grapefruit juice may increase your level of the hormone ethinyl estradiol if used together, including:

  • acetaminophen
  • ascorbic acid
  • medicines that affect how your liver breaks down other medicines (itraconazole, ketoconazole, voriconazole, and fluconazole)
  • certain HIV medicines (atazanavir, indinavir)
  • atorvastatin
  • rosuvastatin
  • etravirine

Hormonal birth control methods may interact with lamotrigine, an anti-seizure medicine used for epilepsy. This may increase the risk of seizures, so your healthcare professional may need to adjust the dose of lamotrigine.

Women on thyroid replacement therapy may need increased doses of thyroid hormone.

Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine.

What are the possible side effects of Xulane?

Xulane may cause serious side effects, including:

  • Blood clots. Like pregnancy, hormonal birth control methods increase the risk of serious blood clots, especially in women who have other risk factors, such as smoking, obesity, or age greater than 35. This increased risk is highest when you first start using hormonal birth control and when you restart the same or different hormonal birth control after not using it for a month or more. Some studies have reported that women who use norelgestromin and ethinyl estradiol transdermal system have a higher risk of getting a blood clot. Talk with your healthcare professional about your risk of getting a blood clot before using Xulane or deciding which type of birth control is right for you.

It is possible to die or be permanently disabled from a problem caused by a blood clot, such as a heart attack or a stroke. Some examples of serious blood clots are blood clots in the:

  • legs (deep vein thrombosis)
  • lungs (pulmonary embolus)
  • eyes (loss of eyesight)
  • heart (heart attack)
  • brain (stroke)

Call your healthcare professional right away if you have:

  • leg pain that will not go away
  • sudden shortness of breath
  • sudden blindness, partial or complete
  • severe pain or pressure in your chest
  • sudden, severe headache unlike your usual headaches
  • weakness or numbness in an arm or leg, or trouble speaking
  • yellowing of the skin or eyeballs

Other serious risks include:

  • liver problems including liver tumors
  • gallbladder disease
  • high blood pressure

The most common side effects of Xulane are:

  • breast symptoms (discomfort, swelling, or pain)
  • nausea
  • headache
  • skin irritation, redness, pain, swelling, itching or rash at the patch application site
  • stomach pain
  • pain during menstruation
  • vaginal bleeding and menstrual disorders, such as spotting or bleeding between periods
  • mood, affect and anxiety disorders

Some women have spotting or light bleeding, breast tenderness, or feel sick to their stomach during norelgestromin and ethinyl estradiol transdermal system use. If these symptoms occur, do not stop using the Xulane patch. The problem will usually go away. If it doesn't go away, check with your healthcare professional.

Less common side effects are:

  • acne
  • less sexual desire
  • bloating or fluid retention
  • blotchy darkening of your skin, especially your face
  • high blood sugar, especially in women with diabetes
  • high fat (cholesterol, triglycerides) levels in the blood
  • depression, especially if you have had depression in the past. Call your healthcare professional immediately if you have any thoughts of harming yourself.
  • problems tolerating contact lenses
  • weight gain

Tell your healthcare professional about any side effect that bothers you or that does not go away.

These are not all the possible side effects of Xulane. For more information, ask your healthcare professional or pharmacist.

What should I know about my period when using Xulane?

  • When you use Xulane, you may have bleeding and spotting between periods called unplanned bleeding. Such bleeding may be temporary and usually does not indicate any serious problems. It is important to continue using the patch on schedule. If the unplanned bleeding or spotting is heavy or lasts for more than a few days, you should discuss this with your healthcare professional.

What if I miss my scheduled period when using Xulane?

  • Some women miss periods on hormonal birth control, even when they are not pregnant. However, if you go 2 or more months in a row without a period, or you miss your period after a month where you did not use all of your patches correctly, or you have symptoms associated with pregnancy, such as morning sickness or unusual breast tenderness, call your healthcare professional because you may be pregnant. Stop taking Xulane if you are pregnant.

How do I use Xulane after childbirth?

  • If you are not breastfeeding, wait 4 weeks before using Xulane and use a non-hormonal contraceptive method of birth control, such as a condom and spermicide or diaphragm and spermicide, for the first 7 days of your first cycle only. If you have had sex since your baby was born, wait for your first period, or see your healthcare provider to make sure you are not pregnant before starting Xulane.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

This is not all of the information you should read prior to using Xulane. Please click here to see Patient Information and full Prescribing Information.

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IMPORTANT SAFETY INFORMATION Prescribing Information

Boxed WARNING

What is the most important information I should know about Xulane?

Do not use Xulane if you smoke cigarettes and are over 35 years old. Smoking increases your risk of serious cardiovascular side effects from hormonal birth control methods, including death from heart attack, blood clots or stroke. This risk increases with age and the number of cigarettes you smoke.

IMPORTANT SAFETY INFORMATIONPrescribing Information

Boxed WARNING

What is the most important information I should know about Xulane?

Do not use Xulane if you smoke cigarettes and are over 35 years old. Smoking increases your risk of serious cardiovascular side effects from hormonal birth control methods, including death from heart attack, blood clots or stroke. This risk increases with age and the number of cigarettes you smoke.

Women 15 to 44 years of age who use Xulane may have an increased risk of blood clots compared to women who use certain birth control pills.

You will be exposed to about 60% more estrogen if you use Xulane than if you use a typical birth control pill containing 35 micrograms of estrogen. In general, increased estrogen may increase the risk of side effects, including blood clots.

See full Prescribing Information for complete Boxed WARNING.

Who should not use Xulane?

Do not use Xulane if you:

  • Smoke and are over 35 years old
  • Have or have had blood clots in your arms, legs, eyes or lungs
  • Have an inherited problem that makes your blood clot more than normal
  • Have had a stroke
  • Have had a heart attack
  • Have certain heart valve problems or heart rhythm problems that can cause blood clots to form in the heart
  • Have high blood pressure that medicine cannot control
  • Have diabetes with kidney, eye, nerve, or blood vessel damage
  • Have had certain kinds of severe migraine headaches with aura, numbness, weakness or changes in vision, or have any migraine headaches if you are over age 35
  • Have liver disease, including liver tumors (benign or cancerous)
  • Have unexplained vaginal bleeding
  • Are pregnant or think you may be pregnant. However, Xulane is not known to cause birth defects when used by accident during pregnancy.
  • Have had breast cancer or any cancer that is sensitive to female hormones

Hormonal birth control methods may not be a good choice for you if you have ever had jaundice (yellowing of the skin or eyes) caused by pregnancy or related to previous use of hormonal birth control.

Tell your healthcare professional if you have ever had any of the above conditions. Your healthcare professional may recommend another method of birth control.

Before you use Xulane tell your healthcare professional:

  • About all your medical conditions.
  • If you are pregnant or think you are pregnant.
  • If you are scheduled for surgery. Xulane may increase your risk of blood clots after surgery. You should stop using your Xulane patch at least 4 weeks before you have surgery and not restart it until at least 2 weeks after your surgery.
  • If you are or will be inactive or immobilized for a long period of time.
  • If you are scheduled for any laboratory tests. Certain blood tests may be affected by hormonal birth control methods.
  • Are breastfeeding or plan to breastfeed. Hormonal birth control methods that contain estrogen, like Xulane, may decrease the amount of milk you make. A small amount of hormones from the Xulane patch may pass into your breast milk. Consider another method of birth control until you are ready to stop breastfeeding.
  • If you plan to start or resume Xulane after child birth. The risk of blood clots is increased for a period of time after childbirth. If you are not breastfeeding, wait 4 weeks before using Xulane.

Tell your healthcare professional about all medicines and herbal products that you take.

Some medicines and herbal products may make hormonal birth control less effective, including, but not limited to:

  • certain seizure medicines (carbamazepine, felbamate, oxcarbazepine, phenytoin, rufinamide, and topiramate)
  • aprepitant
  • barbiturates
  • bosentan
  • griseofulvin
  • certain combinations of HIV medicines (nelfinavir, ritonavir, ritonavir-boosted protease inhibitors)
  • certain non-nucleoside reverse transcriptase inhibitors (nevirapine)
  • rifampin and rifabutin
  • St. John’s wort

Use another birth control method (such as a condom and spermicide or diaphragm and spermicide) when you take medicines that may make the Xulane patch less effective.

Some medicines and grapefruit juice may increase your level of the hormone ethinyl estradiol if used together, including:

  • acetaminophen
  • ascorbic acid
  • medicines that affect how your liver breaks down other medicines (itraconazole, ketoconazole, voriconazole, and fluconazole)
  • certain HIV medicines (atazanavir, indinavir)
  • atorvastatin
  • rosuvastatin
  • etravirine

Hormonal birth control methods may interact with lamotrigine, an anti-seizure medicine used for epilepsy. This may increase the risk of seizures, so your healthcare professional may need to adjust the dose of lamotrigine.

Women on thyroid replacement therapy may need increased doses of thyroid hormone.

Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine.

What are the possible side effects of Xulane?

Xulane may cause serious side effects, including:

  • Blood clots. Like pregnancy, hormonal birth control methods increase the risk of serious blood clots, especially in women who have other risk factors, such as smoking, obesity, or age greater than 35. This increased risk is highest when you first start using hormonal birth control and when you restart the same or different hormonal birth control after not using it for a month or more. Some studies have reported that women who use norelgestromin and ethinyl estradiol transdermal system have a higher risk of getting a blood clot. Talk with your healthcare professional about your risk of getting a blood clot before using Xulane or deciding which type of birth control is right for you.

It is possible to die or be permanently disabled from a problem caused by a blood clot, such as a heart attack or a stroke. Some examples of serious blood clots are blood clots in the:

  • legs (deep vein thrombosis)
  • lungs (pulmonary embolus)
  • eyes (loss of eyesight)
  • heart (heart attack)
  • brain (stroke)

Call your healthcare professional right away if you have:

  • leg pain that will not go away
  • sudden shortness of breath
  • sudden blindness, partial or complete
  • severe pain or pressure in your chest
  • sudden, severe headache unlike your usual headaches
  • weakness or numbness in an arm or leg, or trouble speaking
  • yellowing of the skin or eyeballs

Other serious risks include:

  • liver problems including liver tumors
  • gallbladder disease
  • high blood pressure

The most common side effects of Xulane are:

  • breast symptoms (discomfort, swelling, or pain)
  • nausea
  • headache
  • skin irritation, redness, pain, swelling, itching or rash at the patch application site
  • stomach pain
  • pain during menstruation
  • vaginal bleeding and menstrual disorders, such as spotting or bleeding between periods
  • mood, affect and anxiety disorders

Some women have spotting or light bleeding, breast tenderness, or feel sick to their stomach during norelgestromin and ethinyl estradiol transdermal system use. If these symptoms occur, do not stop using the Xulane patch. The problem will usually go away. If it doesn't go away, check with your healthcare professional.

Less common side effects are:

  • acne
  • less sexual desire
  • bloating or fluid retention
  • blotchy darkening of your skin, especially your face
  • high blood sugar, especially in women with diabetes
  • high fat (cholesterol, triglycerides) levels in the blood
  • depression, especially if you have had depression in the past. Call your healthcare professional immediately if you have any thoughts of harming yourself.
  • problems tolerating contact lenses
  • weight gain

Tell your healthcare professional about any side effect that bothers you or that does not go away.

These are not all the possible side effects of Xulane. For more information, ask your healthcare professional or pharmacist.

What should I know about my period when using Xulane?

  • When you use Xulane, you may have bleeding and spotting between periods called unplanned bleeding. Such bleeding may be temporary and usually does not indicate any serious problems. It is important to continue using the patch on schedule. If the unplanned bleeding or spotting is heavy or lasts for more than a few days, you should discuss this with your healthcare professional.

What if I miss my scheduled period when using Xulane?

  • Some women miss periods on hormonal birth control, even when they are not pregnant. However, if you go 2 or more months in a row without a period, or you miss your period after a month where you did not use all of your patches correctly, or you have symptoms associated with pregnancy, such as morning sickness or unusual breast tenderness, call your healthcare professional because you may be pregnant. Stop taking Xulane if you are pregnant.

How do I use Xulane after childbirth?

  • If you are not breastfeeding, wait 4 weeks before using Xulane and use a non-hormonal contraceptive method of birth control, such as a condom and spermicide or diaphragm and spermicide, for the first 7 days of your first cycle only. If you have had sex since your baby was born, wait for your first period, or see your healthcare provider to make sure you are not pregnant before starting Xulane.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

This is not all of the information you should read prior to using Xulane. Please click here to see Patient Information and full Prescribing Information.

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